J Am Acad Dermatol. Br J Dermatol. Imiquimod: potential risk of an immunostimulant. Australas J Dermatol. Imiquimod, a patient-applied immune-response modifier for treatment of external genital warts. Antimicrob Agents Chemother. Vitiligo-like hypopigmentation associated with imiquimod treatment of genital warts.
Clin Infect Dis. Current modalities and new advances in the treatment of basal cell carcinoma. Int J Dermatol. Current and potential uses of imiquimod. South Med J. Treatment of extramammary Paget disease with topical imiquimod cream: case report and literature review.
Spontaneous regression of keratoacanthoma can be promoted by topical treatment with imiquimod cream. J Eur Acad Dermatol Venereol.
First case series on the use of imiquimod for morphoea. HPV Study Group. Human PapillomaVirus. Arch Dermatol. Rapid improvement of human orf ecthyma contagiosum with topical imiquimod cream: report of four complicated cases. J Dermatolog Treat. Imiquimod in the treatment of actinic keratosis. A meta-analysis of randomized controlled trials.
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A randomized, controlled, safety study using imiquimod for the topical treatment of anogenital warts in HIV-infected patients. Viral and nonviral uses of imiquimod: a review. J Cutan Med Surg. Evaluation of the effectiveness of imiquimod and 5-fluorouracil for the treatment of actinic keratoses: critical review and meta-analysis of efficacy studies.
Imiquimod for actinic keratoses: systematic review and meta-analysis. J Invest Dermatol. Pediatr Dermatol. Topical immunomodulators for the treatment of external genital warts, cutaneous warts and molluscum contagiosum. Clin Exp Dermatol. Dermatol Surg. J Dermatol. Imiquimod therapy for elastosis perforans serpiginosa. Am J Obstet Gynecol.
Australasian Multicentre Trial Group. Imiquimod: an effective alternative for the treatment of invasive cutaneous squamous cell carcinoma. Eruptive epidermoid cysts resulting from treatment with imiquimod. Some people might need extra monitoring while using Aldara cream.
Make sure your doctor knows if you:. It's important to follow the instructions given by your doctor, as well as those printed in the information leaflet supplied with the cream. Each sachet of cream is for single-use only; do not re-use a sachet once you have opened it. Apply Aldara cream in a thin layer to the warts and rub it in until it vanishes, three times a week for example Monday, Wednesday, Friday before going to bed.
The cream should be left on for 6 to 10 hours each time and then washed off with mild soap and water. Continue treatment until the warts are cleared up to a maximum of 16 weeks per episode of warts.
Uncircumcised men treating warts under the foreskin should pull back the foreskin and wash the area daily to avoid constriction of the foreskin phimosis. If you have any trouble pulling back your foreskin during treatment, or you get skin reactions such as redness, ulceration or hardening of the skin, stop using Aldara and see your doctor.
Apply enough cream to cover the treatment area, including one centimetre of skin surrounding the tumour, and rub it in until it vanishes. Do this five times a week for example Monday to Friday before going to bed. The cream should be left on for 8 hours each time and then washed off with mild soap and water. Continue treatment for 6 weeks. The first step to getting an imiquimod cream prescription is to consult with a medical provider.
One cannot just buy podofilox online or get podofilox OTC in the United States from a pharmacy as it is a medication that requires a prescription before it can be dispensed. Because of this restriction, the first step to getting a podofilox cream prescription is consulting a licensed medical provider. Basal cell skin cancer BCC Imiquimod cream is approved in the UK for the treatment of superficial basal cell skin cancers measuring up to 2cm across.
It can be used on your chest, neck, arms or legs including hands and feet. One major side effect: Imiquimod produces intense itching and scratching. Your Medicine Aldara cream contains the active ingredient imiquimod. Imiquimod is an immune response modifier. It activates immune cells in the body. The immune cells then proceed to kill and remove the virus-infected or cancer cells.
Note that this may not provide an exact translation in all languages. Home arrow-right-small-blue Topics A—Z arrow-right-small-blue Imiquimod. Imiquimod is an immune response modifier. Generic forms of imiquimod cream are also available. It was first approved for use in genital warts. It may also be helpful in the unapproved treatment of common warts once they have been thinned down by other means , plane warts, and herpes simplex.
Experimentally it has been successful in reducing some keloid scars, granuloma annulare , vitiligo , melanoma in situ lentigo maligna type and, in combination with diphencyprone , metastatic melanoma see topical and intralesional immunotherapy for melanoma. Although sometimes prescribed for molluscum contagiosum , clinical trials have not shown imiquimod to be of benefit, and it use for this indication is not recommended.
Before starting, a biopsy may be performed to confirm the diagnosis. Imiquimod is particularly useful for field changes, superficial skin cancers with poorly defined margins, and in areas where surgery or other treatments may be difficult, complicated or otherwise undesirable, especially the face and lower legs.
Imiquimod works by stimulating the immune system to release a number of chemicals called cytokines , which are important in fighting viruses and destroying cancer cells. When used to treat skin cancers and pre-cancerous lesions it results in inflammation , which destroys the lesion. The degree of inflammation is quite variable from person to person, in part due to the type of skin lesion and in part due to genetic factors.
The imiquimod should be applied less often if the reaction is excessive, and more often if no reaction occurs perhaps accompanied by a topical retinoid to enhance absorption of imiquimod into the skin.
The course can be repeated, and treatment is sometimes continued for up to 16 weeks. Treatment should be carefully monitored, because the cream may need to be applied more or less frequently than originally planned or for a shorter or longer course, depending on response. Once the inflammation has settled there is generally a good or excellent cosmetic result with little scarring.
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